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T. Rajji

2 papers in the library · publishing 2021-2025

Papers

The effects of naturalistic cannabis use on cognition and subjective experience in older adults with normal cognitive function

Journal of Psychopharmacology November 3, 2025 P. di Ciano, B. Le Foll, S. Zhao et al.

Older adults aged 65–78 who smoked their preferred legal cannabis with an average THC content of 18.7% showed decreased performance on the trail making test (versions A and B) 60 minutes after smoking, compared to when they were sober. However, the percentage of words retained in a verbal free recall test was significantly higher after cannabis, apparently due to a reversal in performance decrement. Smoked cannabis produced robust subjective drug effects. Correlations between blood THC levels and cognitive performance at 60 and 210 minutes were unclear. The findings suggest that older adults who use cannabis may show decrements on only some cognitive tests, along with marked changes in subjective experience.

DOI: 10.1177/02698811251370975 (opens in new tab) Medicine Psychology

Enhancing Cognition in Older Persons with Depression or Anxiety with a Combination of Mindfulness-Based Stress Reduction (MBSR) and Transcranial Direct Current Stimulation (tDCS): Results of a Pilot Randomized Clinical Trial

Mindfulness October 5, 2021 Heather J. Brooks, H. Oughli, Lojine Y. Kamel et al.

Combining Mindfulness-Based Stress Reduction (MBSR) with transcranial direct current stimulation (tDCS) is feasible and safe for older adults with subjective memory complaints and symptoms of depression or anxiety. In a pilot double-blind randomized sham-controlled trial, 26 participants received either active or sham tDCS during MBSR sessions. The largest effect sizes for active versus sham tDCS were for everyday mindfulness and social functioning, though these were not statistically significant. At-home adherence and in-class attendance varied. The authors suggest tDCS may enhance MBSR by transferring meditative learning into everyday mindfulness.

DOI: 10.1007/s12671-021-01764-9 (opens in new tab) Full text (opens in new tab) Medicine Psychology