Cannabis, psychosis and the thalamus: a theoretical review.
Neuroscience and Biobehavioral Reviews May 1, 2013 Zoran Vukadinovic, Merrill S Herman, Ivana Rosenzweig
The role of cannabis in the etiology of schizophrenia has been documented as possibly the strongest environmental risk factor. However, the pathomechanism whereby cannabis use increases this risk has not yet been identified. We argue that this pathomechanism may involve direct effects of exogenous cannabinoids on T-type calcium channels in the thalamus. These channels are crucial for...