Changes in neuroticism and values after naturalistic use of psychedelics and MDMA: a prospective survey study
Journal of Affective Disorders Reports July 1, 2026 Abigail E. Calder, Vincent J Diehl, Bernd Hinney et al.
Background Serotonergic psychedelics and MDMA may improve mental health through reductions in neuroticism and changes in personal values. While decreases in neuroticism following serotonergic psychedelics are sometimes observed, it is unclear which facets of neuroticism respond the most, and MDMA remains understudied. People also report value shifts after psychedelic experiences, but...