Ephenidine: A new psychoactive agent with ketamine-like NMDA receptor antagonist properties
Neuropharmacology August 10, 2016 Heather Kang, Pojeong Park, Zuner A. Bortolotto et al. 29 citations
H-MK-801 binding (Ki: 66 nM), implying that it acts at the PCP site of the N-methyl-d-aspartate (NMDA) receptor. It also showed modest activity at dopamine (379 nM) and noradrenaline (841 nM) transporters and at sigma 1 (629 nM) and sigma 2 (722 nM) binding sites. In experiments of extracellular recording of field excitatory postsynaptic potentials (fEPSPs) from area CA1 of rat hippocampal...