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Oleg A. Yakovlev

2 papers in the library · 38 citations · publishing 2018-2019

Papers

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Acute behavioral effects of deliriant hallucinogens atropine and scopolamine in adult zebrafish.

Behavioural Brain Research February 1, 2019 Andrey D. Volgin, Oleg A. Yakovlev, Konstantin A. Demin et al.

Atropine and scopolamine are classical muscarinic cholinergic antagonists that exert multiple CNS effects. Belonging to a group of deliriant hallucinogens, these drugs induce delirium-like hallucinations, hyperactivity, altered affective states and amnesia. However, as deliriants remain the least studied group of hallucinogens, their complex and poorly understood profiles necessitate further...

Understanding Central Nervous System Effects of Deliriant Hallucinogenic Drugs through Experimental Animal Models

ACS Chemical Neuroscience September 25, 2018 Andrey D. Volgin, Oleg A. Yakovlev, Konstantin A. Demin et al. 38 citations

Hallucinogenic drugs potently alter human behavior and have a millennia-long history of use for medicinal and religious purposes. Interest is rapidly growing in their potential as CNS modulators and therapeutic agents for brain conditions. Antimuscarinic cholinergic drugs, such as atropine and scopolamine, induce characteristic hyperactivity and dream-like hallucinations and form a separate...

DOI: 10.1021/acschemneuro.8b00433 (opens in new tab) Hallucinogen Cholinergic Pharmacology Parasympatholytic +4