Metabolic Fate of Hallucinogenic NBOMes
Chemical Research in Toxicology December 16, 2015 Sebastian Leth-Petersen, Charlotte Gabel‐Jensen, Nic Gillings et al. 43 citations
2,5-Dimethoxy-N-benzylphenethylamines (NBOMes) are very potent 5-HT2AR agonists. Illicit use of these psychedelic compounds has emerged in recent years, and several fatalities have been linked to their recreational use. In its [(11)C]-labeled form, one NBOMe (25B-NBOMe) was recently developed as a PET-ligand for clinical investigations of 5HT2AR ([(11)C]Cimbi-36). Herein, we have identified the...