Psilocybin sex-dependently reduces alcohol consumption in C57BL/6J mice
Frontiers in Pharmacology January 4, 2023 Kenneth Alper, Janelle Cange, Ria Sah et al. 39 citations
The classical psychedelic psilocybin is of interest as a treatment for alcohol use disorder (AUD). This study investigated the effects of psilocybin on voluntary ethanol consumption in adult male and female C57BL/6J mice administered saline or psilocybin intraperitoneally as a single dose of 0.1, 0.5, 1.0 or 2.0 mg/kg and provided 20% ethanol utilizing a two-bottle choice alcohol drinking...