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Paul Stokes

1 paper in the library · 62 citations · publishing 2011

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History of cannabis use is not associated with alterations in striatal dopamine D 2 /D 3 receptor availability

Journal of Psychopharmacology September 2, 2011 Paul Stokes, Alice Egerton, Ben Watson et al. 62 citations

Cannabis use in adolescence is emerging as a risk factor for the development of psychosis. In animal studies, Δ9-tetrahydrocannabinol (THC), the psychoactive component of cannabis, modulates striatal dopaminergic neurotransmission. Alterations in human striatal dopaminergic function have also been reported both in psychosis and in stimulant use. We sought to examine whether striatal dopamine...