Background: Off-label use of intravenous ketamine (IVK) for depression is a widespread practice with limited regulation in the United States. There is an urgent need for current, evidence-informed treatment guidelines to facilitate patient safety, clinical decision-making, and care quality in real-world contexts. Methods: The American Society of Ketamine Physicians, Psychotherapists and...
PsychedelicsMay 1, 2026Madeleine Cluck, Alison B. Purcell, Zuzana Kazan et al.
There is currently an ongoing resurgence in research on the therapeutic potential of psychedelics for psychiatric conditions. Psychedelic-assisted therapy (PAT) differs from most current forms of psychiatric treatment in two primary domains: its requirement for fewer doses (often just one), and its documented ability to promote profound insights, introspection, and cognitive shifts. Autism...