Reduced functional segregation between the default mode network and the executive control network in healthy older adults: A longitudinal study
Neuroimage March 19, 2016 Kwun Kei Ng, June C. Lo, Joseph K.W. Lim et al. 237 citations
The effects of age on functional connectivity (FC) of intrinsic connectivity networks (ICNs) have largely been derived from cross-sectional studies. Far less is known about longitudinal changes in FC and how they relate to ageing-related cognitive decline. We evaluated intra- and inter-network FC in 78 healthy older adults two or three times over a period of 4years. Using linear mixed modeling...