Potentiation of 5-methoxy-N,N-dimethyltryptamine-induced hyperthermia by harmaline and the involvement of activation of 5-HT1A and 5-HT2A receptors.
Neuropharmacology February 1, 2015 Xi-Ling Jiang, Hong-Wu Shen, Ai-Ming Yu 26 citations
5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) and harmaline are serotonin (5-HT) analogs often abused together, which alters thermoregulation that may indicate the severity of serotonin toxicity. Our recent studies have revealed that co-administration of monoamine oxidase inhibitor harmaline leads to greater and prolonged exposure to 5-HT agonist 5-MeO-DMT that might be influenced by cytochrome...
DOI: 10.1016/j.neuropharm.2014.10.013 (opens in new tab)
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Thermoregulation
Temperature control
Thermal regulation
Drug interaction
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