Intravenous self-administration of (-)-cathinone and 2-amino-1-(2,5-dimethoxy-4-methyl)phenylpropane in rhesus monkeys.
T Yanagita
Drug and Alcohol Dependence June 1986 DOI: 10.1016/0376-8716(86)90004-9 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Animal self-administration study Peer reviewed |
|---|---|
| Population | Rhesus monkeys |
| Intervention | (-)-Cathinone |
| Key points | The text reports that rhesus monkeys self-administered (-)-cathinone continuously, indicating reinforcing effects for this khat constituent; the result was briefly reported elsewhere. Results for STP (DOM) are not stated in the abstract. |
Abstract
The reinforcing effects of (-)-cathinone, a pharmacologically active ingredient of khat, and 2-amino-1-(2,5-dimethoxy-4-methyl)phenylpropane ((STP) (DOM)), a hallucinogenic psychotomimetic, were studied by intravenous self-administration experiments in rhesus monkeys. Among the experiments described in this paper, the result of continuous self-administration of (-)-cathinone was briefly reported elsewhere. T. Yanagita, Studies on Cathinones, NIDA Research Monograph 27, Proceedings of 41st Annual Scientific Meeting of the Committee on Problems of Drug Dependence, 1979, pp. 326-327.
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