What is the efficacy of low-dose ketamine for treating depression and other mental health conditions?
Zenodo (CERN European Organization for Nuclear Research) October 21, 2026 preprint DOI: 10.5281/zenodo.23540429 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Intervention | Ketamine |
|---|---|
| Topics | Depression Esketamine Ketamine |
| Key points | Reports that ketamine has moderate efficacy as a rapid-acting treatment for treatment-resistant depression, including bipolar depression, with evidence supporting use mainly in treatment-resistant cases. Notes that monitoring and cautious patient selection are needed because long-term safety data are limited. |
Abstract
Ketamine shows moderate efficacy as a rapid-acting treatment for treatment-resistant depression, including bipolar depression, with evidence supporting its use mainly in treatment-resistant cases. Monitoring and cautious patient selection are necessary due to limited long-term safety data.