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Who seeks ayahuasca and why? Participant profiles and engagement patterns in a community-based practice (2014-2026)

Francisco Castellanos-Fernández, Francina Solé-Mauri

Zenodo (CERN European Organization for Nuclear Research) October 16, 2026 preprint DOI: 10.5281/zenodo.23540472 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Retrospective observational analysis of administrative records
Sample size 1,134
Population Participants in a community ayahuasca practice near Barcelona, Spain, recorded across registration (N=1,134), health intake (N=359), and ceremony attendance (N=309) datasets
Intervention Ayahuasca
Duration Registration records 2014-2025; health intake forms 2025; ceremony attendance logs 2023-2026
Topics Ayahuasca
Key findings Participants were mostly stable middle-aged adults seeking personal growth (72.5%) rather than symptom relief, with high life satisfaction (mean 7.4/10) and low current psychological disorder (10.3%). Participation was typically occasional: 54% attended a single ceremony and median attendance duration was 0.7 years, with no sign of escalating involvement. About 9% showed higher clinical need, and no difference in engagement duration across health-based subgroups was detected.

Abstract

Background: Community-based ayahuasca use has spread across Europe, often accompanied by public concern about intensive or escalating involvement. Yet who takes part, what brings them, and how long they stay are poorly documented. Describing these patterns is a prerequisite for proportionate harm reduction, benefit enhancement, and policy.

Aims: To describe the demographics, motivations, and mental and physical health of participants in a long-running community practice; to describe engagement over time using attendance behaviour rather than self-report; and to test whether participants form distinct subgroups.

Methods: Retrospective analysis of three administrative datasets from La Maloka, a non-religious community ayahuasca practice near Barcelona operating since 2014: registration records (N=1,134; 2014-2025), health intake forms (N=359; 2025), and ceremony attendance logs (N=309; 2023-2026). We used descriptive statistics, survival analysis of how long participants kept attending, and cluster analysis to identify participant subgroups.

Results: Participants were mostly middle-aged adults (mean 46.7 years) reporting high life satisfaction (mean 7.4/10) and low current psychological disorder (10.3%), yet most (63.8%) had previously been in psychological therapy, a profile combining prior engagement with psychotherapy and present stability. Personal growth, not symptom relief, was the dominant motivation (72.5%), and prior psychedelic experience was common (80.5%). Participation was typically occasional: just over half (54%) attended a single ceremony, the median time participants kept attending was 0.7 years, and there was no sign of escalating participation. Only about 9% of participants showed a profile of higher clinical need, and no difference in engagement duration across health-based subgroups was detected.

Conclusions: In this setting, ayahuasca drew stable adults pursuing personal development rather than clinical treatment, and participation was typically occasional rather than intensifying. A small minority presenting clinical complexity may warrant closer attention, supporting differentiated rather than uniform community protocols. Routinely kept records can describe who participates and track engagement over time, offering a practical monitoring approach for other community groups.

Comparable studies

Other observational and cohort studies on ayahuasca, most cited first.

Study Year Design Participants
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
The Psychedelic State Induced by Ayahuasca Modulates the Activity and Connectivity of the Default Mode Network Experienced subjects 2015 Observational cohort n = 10
Human Psychopharmacology of Hoasca, A Plant Hallucinogen Used in Ritual Context in Brazil Long-term members of a syncretic church that uses hoasca as a psychoactive sacrament... 1996 Observational cohort with matched controls n = 30
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population 2013 Observational study
Personality, Psychopathology, Life Attitudes and Neuropsychological Performance among Ritual Users of Ayahuasca: A Longitudinal Study Regular ayahuasca users and active controls in non-ayahuasca religions 2012 Observational cohort n = 242

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