Difficulties with emotion regulation, mindfulness, and substance use disorder severity: the mediating role of self-regulation of attention and acceptance attitudes.

Background: Theoretical frameworks postulate that mindfulness represents a relevant therapeutic process in substance use disorders (SUDs), especially in treating difficulties with emotion regulation (DER). Nonetheless, it remains unclear how mindfulness dimensions, particularly self-regulation of attention and acceptance attitudes, are implicated in the well-validated relationship between DER and SUDs. It is also uncertain whether mindfulness is considered a common protective factor for SUDs.

Objectives: To investigate the mediating role of mindfulness in the relationships between DER and SUDs among treatment-seeking patients with alcohol use disorder (AUD).

Methods: Two related domains of mindfulness were evaluated: (a) self-regulation of attention (Mindful Attention Awareness Scale, MAAS) and (b) acceptance attitudes (Five Facet Mindfulness Questionnaire, FFMQ, nonjudging, and nonreactivity subscales)). Two-hundred and forty-four (149 males and 95 females) participants with AUD were assessed. Mindfulness, DER, and SUD severity (alcohol, benzodiazepines, and other drugs) were assessed after a 2-week detoxification period. Three independent multiple parallel mediational models, controlling for the heterogeneity of sample characteristics, were proposed.

Results: MAAS and FFMQ nonjudging were significant mediators of the relationship between DER and AUD severity. Mindfulness dimensions and DER were not related to other drug use disorders. DER represented a relevant factor in explaining the severity of benzodiazepine use disorder, although mindfulness was not significantly related to it.

Conclusion: Mindfulness appears to be a protective factor for DER effects on AUD. Future research should evaluate additional dysfunctional processes to clarify how unique dimensions are implicated in the development and maintenance of different SUDs.