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Chiricaspi (Brunfelsia grandiflora, Solanaceae), a Pharmacologically Promising Plant.

Carmen X Luzuriaga-Quichimbo, Míriam Hernández del Barco, José Blanco-Salas, Carlos E Cerón-Martínez, Trinidad Ruiz-Téllez

Plants August 18, 2018 DOI: 10.3390/plants7030067 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Ethnography Peer reviewed
Population Canelo-Kichwa Amazonian community in Pastaza province, Ecuador
Topics Ayahuasca
Keywords Amazonian Brunfelsia Ecuador Activity Bioproduct Drug discovery Ethnobotanic Scopoletin Validation
Key findings Describes ancestral Canelo-Kichwa practices involving chiricaspi (Brunfelsia grandiflora s.l.) that remain in force, and reports that bibliographic and database checks identified activity and chemical components. The authors propose routes for new bioproducts and argue that in silico drug design based on this traditional knowledge could advance childbirth, anesthesiology, and neurology.

Abstract

This study's objective was to evaluate the rescued traditional knowledge about the chiricaspi (Brunfelsia grandiflora s.l.), obtained in an isolated Canelo-Kichwa Amazonian community in the Pastaza province (Ecuador). This approach demonstrates well the value of biodiversity conservation in an endangered ecoregion. The authors describe the ancestral practices that remain in force today. They validated them through bibliographic revisions in data megabases, which presented activity and chemical components. The authors also propose possible routes for the development of new bioproducts based on the plant. In silico research about new drug design based on traditional knowledge about this species can produce significant progress in specific areas of childbirth, anesthesiology, and neurology.

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Citations in the library

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