Interrupting the Psychedelic Experience Through Contextual Manipulation to Study Experience Efficacy.
Leor Roseman, David Erritzøe, David Nutt, Robin Carhart-Harris, Christopher Timmermann
JAMA Network Open July 1, 2024 DOI: 10.1001/jamanetworkopen.2024.22181 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Quality improvement study Peer reviewed |
|---|---|
| Topics | Psychedelic-assisted therapy |
| Keywords | Psychedelic treatment Psychedelic healing Psychedelic intervention Contextual factors Environmental influence Setting effects Situational context Experiential context Mental well-being Mental health Psychological health Emotional health Therapeutic potential Healing potential Treatment efficacy Curative promise |
| Citations | 12 |
| Key points | Interruptions during psychedelic therapy are associated with lower ratings of intensity of experience. |
Abstract
This quality improvement study investigates the association of interruptions during psychedelic therapy with ratings of intensity of experience.
Citations in the library
Cited by 8
- The intensity of the psychedelic experience is reliably associated with clinical improvements: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews May 1, 2025
- Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: Α factorial dose-escalation study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie March 1, 2025
- A reflection on paradigmatic tensions within the FDA advisory committee for MDMA-assisted therapy. Journal of Psychopharmacology April 1, 2025
- The science of psychedelic medicine. Nature Medicine February 6, 2026
- How to set up a psychedelic study: Unique considerations for research involving human participants. Neuroscience & Biobehavioral Reviews July 1, 2026
and 3 more in the library
Cites 6
- Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression Frontiers in Pharmacology January 17, 2018
- Psychometric Evaluation of the Altered States of Consciousness Rating Scale (OAV) PLoS One August 31, 2010
- Psychedelic-Assisted Psychotherapy: A Paradigm Shift in Psychiatric Research and Development Frontiers in Pharmacology July 5, 2018
- Human brain effects of DMT assessed via EEG-fMRI. Proceedings of the National Academy of Sciences March 28, 2023
- Effects of DMT on mental health outcomes in healthy volunteers Scientific Reports February 7, 2024
and 1 more in the library