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The Follow-Up Problem in Psilocybin-Assisted Therapy: Integration, Aftercare, and the Missing Standard

Cacho Ernesto

Zenodo (CERN European Organization for Nuclear Research) October 14, 2026 preprint DOI: 10.5281/zenodo.23376467 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Commentary
Topics Psilocybin
Key points Argues that integration, aftercare, and long-term follow-up in psilocybin-assisted therapy remain poorly defined compared with short-term clinical outcome measurement, and identifies gaps and opportunities in moving these practices from trials to real-world implementation in Oregon and Colorado.

Abstract

As psilocybin-assisted therapy becomes increasingly standardized in measuring short-term clinical outcomes, the processes that follow the psychedelic experience remain far less defined. This paper examines integration, aftercare, and long-term follow-up from clinical trials to real-world implementation in Oregon and Colorado, identifying critical gaps and opportunities to better understand, evaluate, and support sustained change.

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  • Argues that integration, aftercare, and long-term follow-up in psilocybin-assisted therapy remain poorly defined compared with short-term outcome measurement.

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