Effects of Mind-Body Training on Personality and Behavioral Activation and Inhibition System According to BDNF Val66Met Polymorphism.
Ye-Ha Jung, Ul Soon Lee, Joon Hwan Jang, Do‐hyung Kang
Psychiatry Investigation May 18, 2016 DOI: 10.4306/pi.2016.13.3.333 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Cross-sectional comparison of meditators and controls Peer reviewed |
|---|---|
| Sample size | 136 |
| Population | Healthy adults: 64 controls and 72 regular meditation practitioners |
| Measures | Neuroticism-Extraversion-Openness (NEO) Five-Factor Inventory, Behavioral Activation System/Behavioral Inhibition System (BAS/BIS) scales |
| Keywords | Behavioral activation system Behavioral inhibition system Mind-body training Neo personality |
| Key findings | Mind-body training was associated with higher Extraversion and Openness and lower BIS across BDNF genotypes, with additional lower Neuroticism and higher BAS-Fun Seeking in Met/Met carriers. The authors argue that these effects differ by BDNF Val66Met genotype, potentially compensating for genotype-specific vulnerable traits. |
Abstract
Objective: It has been known that mind-body training (MBT) can affect personality and behavior system as well as emotional well-being, but different effects of MBT on them has not been reported according to BDNF genetic polymorphism.
Methods: Healthy subjects consisted of 64 subjects and the MBT group who practiced meditation regularly consisted of 72 practitioners. Participants completed neuroticism-extraversion-openness (NEO) Five-Factor Inventory and Behavioral Activation System/Behavioral Inhibition System (BAS/BIS) scales. All subjects were genotyped for the BDNF Val66Met polymorphism.
Results: In the same genotypes of the BDNF Val/Val+Val/Met group, MBT group showed the increased Extraversion (p=0.033) and the increased Openness to Experience (p=0.004) compared to the control group. Also, in the same Met/Met carriers, MBT group exhibited the increase of Extraversion (p=0.008), the reduction of Neuroticism (p=0.002), and the increase of Openness to Experience (p=0.008) compared to the control group. In the same genotypes of the BDNF Val/Val+Val/Met group, MBT group showed the decreased BAS-Reward Responsiveness (p=0.016) and the decrease of BIS (p=0.004) compared to the control group. In the BDNF Met/Met group, MBT group increased BAS-Fun Seeking (p=0.045) and decreased BIS (p=0.013) compared to the control group.
Conclusion: MBT would differently contribute to NEO personality and BAS/BIS according to BDNF genetic polymorphism, compensating for different vulnerable traits based on each genotype.
Citations in the library
Cited by 2
Cites 7
- Mental Training as a Tool in the Neuroscientific Study of Brain and Cognitive Plasticity Frontiers in Human Neuroscience 2011
- Influence of brain-derived neurotrophic factor and catechol O-methyl transferase polymorphisms on effects of meditation on plasma catecholamines and stress. Stress January 2012
- The effects of mind-body training on stress reduction, positive affect, and plasma catecholamines. Neuroscience Letters July 26, 2010
- Effect of compassion meditation on neuroendocrine, innate immune and behavioral responses to psychosocial stress. Psychoneuroendocrinology 2009
- Attention regulation and monitoring in meditation. Trends in Cognitive Sciences April 1, 2008
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