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Cannabinoids: from pot to lab

Esther Papaseit, Clara Pérez‐mañá, A. P. Pérez-Acevedo, Olga Hladun, M. C. Torres-Moreno, Roberto Muga, Marta Torrens, M. Farré

International Journal of Medical Sciences August 6, 2018 DOI: 10.7150/ijms.27087 (opens in new tab)

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Characteristics Review Peer reviewed
Key findings The review describes how distinctions between natural and synthetic cannabinoids and between recreational and medical use have become blurred, and surveys legal changes, shifting cannabis composition and consumption patterns, the concept of medical cannabis, and synthetic cannabinoids as new psychoactive substances. It also examines serious adverse reactions and intoxications associated with synthetic cannabinoids and recent developments in pharmaceutical cannabinoid research.

Abstract

Cannabis is becoming increasingly present in our society. In recent years, the line between the natural (cannabis) and the synthetic (synthetic cannabinoids), the recreational (cannabis) and the medical (pharmaceutical cannabinoids and medical cannabis) has been crossed. In this paper we review some of the novel aspects of cannabis and cannabinoids in relation to their legal situation, changes in their composition and forms of cannabis use, the concept of medical cannabis, and synthetic cannabinoids as new psychoactive substances (NPS). We have also analyzed serious adverse reactions and intoxications associated with the use of synthetic cannabinoids, as well as the latest developments in the research of pharmaceutical cannabinoids.

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