A framework for harmla alkaloid extraction process development using fuzzy-rough sets feature selection and J48 classification
Farid Abd-Elreheim Badria, Mohamed Z. Habib, Nora Shoaip, Mohammed Mahfouz Elmogy
International Journal of Advanced Computer Research November 11, 2017 DOI: 10.19101/ijacr.2017.733022 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Peer reviewed |
|---|---|
| Intervention | harmine |
| Dose | 25-50 mg; up to 750 mg |
| Citations | 2 |
| Key points | The text states that Peganum harmala seeds act as a CNS stimulant and are poisonous at high doses, and that harmine and related alkaloids are hallucinogens, serotonin antagonists, short-term MAO inhibitors, and CNS stimulants. It reports that 25-50 mg has a cerebral stimulant effect, sometimes with drowsiness for half an hour, while doses up to 750 mg may cause hallucinations whose intensity varies between individuals. |
Abstract
IntroductionPeganum harmala (Zygophyllaceae) is an herb native to the dry area of the Mediterranean east to northern India.The plant originated in Central Asia, but now grows wild in Africa, Middle East, India, South America, Mexico, and Southern USA [1].Seeds of Peganum harmala are growing widespread in Egypt.They are used as an anti-hemorrhoid and central nervous system (CNS) stimulating agent in folk medicine.Seeds stimulate the CNS, cause paralysis and are poisonous in strong doses [2].Harmine and the resembled alkaloids are hallucinogens, serotonin antagonists, short-term monoamine oxidase (MAO) inhibitors and CNS stimulants.Little doses (25-50 mg) have a cerebral stimulant effect.Sometimes, it may cause drowsy state for half hour.Bigger dosages up to 750 mg may cause hallucination.Its intensity changes depending on persons using it [3].