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Corrigendum to "Continuation phase intravenous ketamine in adults with treatment-resistant depression" [J. Affect. Disord. 206 (2016) 300-304].

J. V. Vande Voort, Robert J Morgan, Simon Kung, K. Rasmussen, Jose A Rico, Brian A. Palmer, Kathryn M Schak, S. Tye, Matthew J. Ritter, Mark A Frye, William V Bobo

Journal of Affective Disorders September 27, 2017 correction DOI: 10.1016/j.jad.2017.09.024 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Correction notice
Sample size 5
Population Patients with depressive symptoms who achieved remission during the acute phase of a ketamine study
Intervention Ketamine
Duration 4 weekly continuation phase infusions; post-continuation phase follow-up
Topics Depression Esketamine Ketamine
Key points After correcting a misclassification, 4 of the 5 patients who achieved depressive symptom remission during the acute phase and received four weekly continuation-phase ketamine infusions were positive treatment responders at the end of the post-continuation phase, not all 5 as originally reported. The authors state that their main conclusions are unchanged.

Abstract

We recently became aware of an error in the classification of one study subject's positive treatment response status at the end of the post-continuation phase of this study. We originally reported that all 5 subjects who achieved depressive symptom remission during the acute phase of the study (and thus received 4 weekly continuation phase ketamine infusions) were classified as responders at the end of the post-continuation phase. However, one of these 5 subjects was misclassified as a positive treatment responder at the end of the post-continuation phase. Therefore, only 4 of these 5 patients were positive treatment responders at the end of the post-continuation phase. Although our main conclusions are not changed, we believe that it is our responsibility to report the error and updated results. The authors would like to apologise for any inconvenience caused.

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