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Methylenedioxymethamphetamine (MDMA)-induced toxic leukoencephalopathy: a case report

H. Salem, T. Barton, Taha Ali, Ashley Anderson, A. Teixeira

December 5, 2017 DOI: 10.1080/24750573.2017.1407562 (opens in new tab)

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Study at a glance

AI-extracted from the abstract
Characteristics Case report
Sample size 1
Population A 33-year-old female with a recent history of ecstasy abuse presenting with delirium and cognitive impairment
Topics MDMA
Key findings The authors report a case of a 33-year-old woman with recent ecstasy abuse who presented with delirium and cognitive impairment and was diagnosed with leukoencephalopathy, a link they note has rarely been reported. They review published case reports on the connection between MDMA and leukoencephalopathy.

Abstract

ABSTRACT In recent years, ecstasy has become a very popular recreational drug. To date, very little data is available regarding its toxic side effects. Specifically, reports relating ecstasy use to the clinical diagnosis of leukoencephalopathy are quite rare. In this report, we present an interesting case of a 33-year-old female with a recent history of ecstasy abuse who presented with delirium and cognitive impairment. In addition, we review published case reports that explore the connection between MDMA and leukoencephalopathy.

Comparable studies

Other case reports and case series on MDMA, most cited first.

Study Year Design Participants
'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use 1987 Case series n = 5
Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... 1996 Case series n = 7
'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA 1987 Case series n = 5
A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... 1998 Case study n = 2
Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... 1994 Case series n = 13

Citations in the library

Cites 4

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