Burst suppression electroencephalogram with mushroom poisoning, Amanita pantherina
Yuka Ogawa, Hiromasa Sato, Motoyoshi Yamamoto, Hiroyuki Tada, Takao Hashimoto
Epilepsy & Behavior Case Reports 2015 DOI: 10.1016/j.ebcr.2015.08.001 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A patient with Amanita pantherina poisoning |
| Duration | Recovered without sequelae a week after ingestion |
| Measures | electroencephalography |
| Citations | 7 |
| Key findings | A patient comatose after ingesting Amanita pantherina showed a burst suppression pattern on electroencephalography and recovered without sequelae a week after ingestion. The authors propose that the mushroom's toxins, ibotenic acid and muscimol, may alter central nervous system synaptic transmission and thereby lead to burst suppression. |
Abstract
We report on a patient with Amanita pantherina poisoning who showed a burst suppression pattern on electroencephalography during a comatose state. The patient recovered without sequelae a week after ingestion. Burst suppression pattern is defined as alternating bursts and periods of electrical silence, and it is associated with comatose states of various causes. The major toxins contained in A. pantherina are ibotenic acid, an excitatory amino acid at the glutamate receptors, and muscimol, an agonist of the gamma-aminobutyric acid receptors. Alteration of the synaptic transmission in the central nervous system by these toxins may lead to a burst suppression pattern.