The Yale Manual for Psilocybin-Assisted Therapy of Depression (using Acceptance and Commitment Therapy as a Therapeutic Frame)
Jeffrey Guss, Robert Krause, Jordan Sloshower
August 13, 2020 preprint DOI: 10.31234/osf.io/u6v9y (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Theoretical or philosophical paper |
|---|---|
| Interventions | Psilocybin-assisted therapy Acceptance and Commitment Therapy (ACT) |
| Topics | Depression Psychedelic-assisted therapy Psilocybin |
| Keywords | Psilocybin-assisted therapy Psilocybin therapy Depression treatment Treating depression Act therapy Psychological methods Psychotherapy Therapy manual Comprehensive manual Therapist guide |
| Citations | 86 |
| Key points | Proposes that ACT can serve as a therapeutic framework for psilocybin-assisted therapy of depression. |
Abstract
The Yale Manual for Psilocybin-Assisted Therapy of Depression provides researchers and therapists with methods, structure, and areas to consider regarding the use of psychedelic- assisted therapy in the treatment of Major Depressive Disorder (MDD). In particular, this manual illustrates a mode of utilizing Acceptance and Commitment Therapy (ACT) as a therapeutic framework for psilocybin-assisted therapy of depression.
Comparable studies
Other theoretical and historical papers on psilocybin and psychedelic-assisted therapy, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Theorizing that Psychedelic Assisted Therapy May Play a Role in the Treatment of Trauma-Induced Personality Disorders. | 2024 | Theoretical or philosophical paper | |
| Towards psychedelic apprenticeship: Developing a gentle touch for the mediation and validation of psychedelic-induced insights and revelations. | 2022 | Theoretical or philosophical paper | |
| Psychedelics and Psychotherapy: Cognitive-Behavioral Approaches as Default | 2022 | Theoretical or philosophical paper | |
| The influence of therapists’ first-hand experience with psychedelics on psychedelic-assisted psychotherapy research and therapist training | 2018 | Theoretical or philosophical paper | |
| Psychedelic-Assisted Psychotherapy Practices and Human Caring Science: Toward a Care-Informed Model of Treatment | 2021 | Theoretical or philosophical paper |
Citations in the library
Cited by 70
- The Therapeutic Potential of Psilocybin Molecules May 15, 2021
- Models of Psychedelic-Assisted Psychotherapy: A Contemporary Assessment and an Introduction to EMBARK, a Transdiagnostic, Trans-Drug Model Frontiers in Psychology June 2, 2022
- Psychedelic Knowledge and Opinions in Psychiatrists at Two Professional Conferences: An Exploratory Survey Journal of Psychoactive Drugs August 19, 2021
- Sub-acute effects of psilocybin on EEG correlates of neural plasticity in major depression: Relationship to symptoms Journal of Psychopharmacology June 30, 2023
- Psilocybin for treatment-resistant depression without psychedelic effects: study protocol for a 4-week, double-blind, proof-of-concept randomised controlled trial BJPsych Open July 1, 2023
and 65 more in the library
Cites 21
- Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. The Lancet Psychiatry May 17, 2016
- The entropic brain: a theory of conscious states informed by neuroimaging research with psychedelic drugs Frontiers in Human Neuroscience 2014
- Human hallucinogen research: guidelines for safety. Journal of Psychopharmacology July 1, 2008
- Psychedelics Promote Structural and Functional Neural Plasticity Cell Reports June 1, 2018
- Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action Neuroreport December 1, 1998
and 16 more in the library