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Delta-8- and Delta-9-THC Use Frequency, Use Motives, and Mental Health Outcomes.

Michael J Pellicane, Madison E Quinn, Christian A L Bean, Madeline E Bartek, Luke F Heggeness, Jeffrey A Ciesla

Journal of Psychoactive Drugs 2024 DOI: 10.1080/02791072.2023.2200211 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Cross-sectional survey Longitudinal Peer reviewed
Sample size 363
Population Self-reported delta-8 users
Topics Cannabis
Keywords Delta-8 Cannabinoids Mental health
Key findings Delta-8 use frequency was unrelated to use problems and other mental health outcomes. Coping and conformity motives were associated with greater depression, anxiety, insomnia, and delta-8 use problems, and participants reported coping and enhancement motives more for delta-8 than for cannabis.

Abstract

Use of delta-8-THC ("delta-8") has proliferated after the passage of the 2018 Farm Bill. Yet, research on the mental health effects of this increasingly popular cannabinoid is scant. The current study sought to examine mental health correlates of delta-8 use frequency and motives, investigate whether delta-8 use motives predict use frequency, and compare use motives and problems between delta-8 and traditional cannabis. Participants consisted of 363 self-reported delta-8 users who completed measures of delta-8 use frequency, motives, and problems that were adapted from comparable measures for cannabis, as well as measures of mental health outcomes. Delta-8 use frequency was unrelated to use problems and other mental health outcomes. Delta-8 use frequency was positively associated with social and coping motives, but negatively associated with enhancement and conformity motives. Coping and conformity motives were associated with greater depression, anxiety, insomnia, and delta-8 use problems. Participants were more likely to report coping and enhancement motives for delta-8 use compared to cannabis use, but less likely to report conformity motives. Further longitudinal research is needed to assess causality for associations between delta-8 use frequency, use motives, and mental health outcomes.

Comparable studies

Other cross-sectional and survey studies on cannabis, most cited first.

Study Year Design Participants
Cannabis use before age 15 and subsequent executive functioning 104 chronic cannabis users (49 early-onset before age 15, 55 late-onset after age 15)... 2011 Observational cross-sectional study n = 148
Patterns of simultaneous polysubstance use in drug using university students Drug-using university students 2006 Cross-sectional survey n = 149
Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An Online Survey Online survey respondents 2020 Cross-sectional survey
User perceptions of the benefits and harms of hallucinogenic drug use: A web-based questionnaire study Users of hallucinogenic drugs who completed a web-based questionnaire 2010 Cross-sectional survey n = 600
Illicit Use of LSD or Psilocybin, but not MDMA or Nonpsychedelic Drugs, is Associated with Mystical Experiences in a Dose-Dependent Manner Adults recruited from the MAPS website and newsletter, most reporting use of various... 2012 Cross-sectional survey n = 337

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