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Parasomnias and Sleep-Related Movement Disorders in Older Adults.

Alex Iranzo

Sleep Medicine Clinics June 2022 DOI: 10.1016/j.jsmc.2022.02.005 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Review Peer reviewed
Keywords Anti-iglon5 disease Disorders of arousal Restless legs syndrome Sleep paralysis
Key findings The review highlights that several sleep disorders have distinct features in the elderly: sleep paralysis is rare but familial, disorders of arousal can persist to age 70, and medications like zolpidem may induce sleepwalking and sleep-eating. Most idiopathic RBD patients eventually develop Parkinson disease or dementia with Lewy bodies. Anti-IgLON5 disease affects both NREM and REM sleep, RLS prevalence increases until the sixth decade, and severe periodic limb movements can mimic RBD.

Abstract

Sleep paralysis is rare in the elderly but may occur particularly in families suffering from this phenomenon. In a minority of patients with disorders of arousal, the episodes persist until the age of 70. Zolpidem and other medications may induce sleepwalking and sleep eating-related syndrome. Most patients with idiopathic REM sleep behavior disorder (RBD) eventually develop Parkinson disease and dementia with Lewy bodies. Anti-IgLON5 disease includes abnormal behaviors in both nonrapid eye movement sleep and rapid eye movement sleep (REM) sleep. Restless legs syndrome prevalence increases with age until the sixth decade. A severe form of periodic limb movements in sleep may clinically mimic REM sleep behavior disorder (RBD).