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Review: Meta-analysis on mindfulness-based interventions for adolescents' stress, depression, and anxiety in school settings: a cautionary tale.

Nilija Fulambarkar, B. Seo, A. Testerman, Mitchell Rees, Kimberly Bausback, E. Bunge

Child and Adolescent Mental Health June 28, 2022 DOI: 10.1111/camh.12572 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Meta-analysis Randomized Peer reviewed
Sample size 5,046
Population Adolescents aged 12-18 in school settings
Intervention Mindfulness-based interventions (MBIs)
Topics Anxiety Depression Meditation
Keywords Education
Key findings Across nine randomized trials, school-based mindfulness interventions produced a small significant overall improvement in stress, depression, and anxiety combined (Hedge's g = 0.33). Effects were significant versus inactive controls (g = 0.38) but not versus active controls (g = 0.27). Per symptom, only perceived stress improved significantly (g = 0.55); depression (g = 0.20) and anxiety (g = 0.19) did not improve significantly.

Abstract

Background: Mindfulness-based interventions (MBIs) have been applied in school settings for adolescents with symptoms of stress, depression, and anxiety; however, general conclusions of the efficacy of such interventions remain unclear. This meta-analysis reviewed randomized-controlled MBI trials for stress, depression, and anxiety in school settings.

Methods: One hundred one records were included after removing duplicates. Nine studies met inclusion criteria, totalling 5046 adolescents aged 12-18. Eighteen comparisons between an MBI and a control group were analyzed.

Results: The overall effect for symptoms of the 17 observations including stress, depression, and anxiety resulted in a significant improvement with a small effect size (k = 17, n = 3721, Hedge's g = .33, CI 95% .17-.49 p < .01). Subgroup analysis revealed that when MBIs were compared to an active control group effects were not significant (k = 5, n = 2753, Hedge's g = .27, CI 95% -.03-.57 p = .08), and when compared to an inactive control group the effect was significant with a small effect size (k = 5, n = 1065, Hedge's g = .38, CI 95% .02-.75 p < .05). Analysis of the interventions on a per symptom basis yielded a significant and moderate effect size for perceived stress (k = 7, n = 1116, Hedge's g = .55, CI 95% .31-.79 p < .01); however, there were no significant effects for depression (k = 6, n = 3172, Hedge's g = .20, CI 95% -.05-.44 p < .01) and anxiety (k = 4, n = 837, Hedge's g = .19, CI 95% -.14-.53 p = .25).

Conclusions: The impact of MBIs in school settings for adolescents yielded a significant improvement for stress, but did not for depression and anxiety. The effects were significant when compared to inactive controls, but not when compared to active controls. Implications of these findings are discussed.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

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