The use of mindfulness-based stress reduction (MBSR) for lung cancer patients: protocol for a systematic review and meta-analysis.
Xu Tian, Zhaofei Zhang, Yanfei Jin, Hui Chen, María F. Jiménez Herrera
Annals of Palliative Medicine 2021 DOI: 10.21037/apm-21-194 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Systematic review and meta-analysis protocol Randomized Peer reviewed |
|---|---|
| Intervention | Mindfulness-based stress reduction (MBSR) |
| Topics | Meditation |
| Key findings | The authors state that the effectiveness of MBSR on psychological and physical outcomes in lung cancer patients has not yet been determined, and propose a systematic review and meta-analysis to establish this evidence and inform future psychological interventions and clinical practice. |
Abstract
Background: Mindfulness-based stress reduction (MBSR) intervention has been extensively applied in cancer patients for relieving symptom burden and its effectiveness has also been demonstrated. However, the effectiveness of MBSR on psychological and physical functions in lung cancer patients has not yet been determined. The aim of the present systematic review and meta-analysis seeks to determine the role of MBSR in lung cancer patients.
Methods: A systematic search of PubMed, EMBASE, Cochrane Library, and China National Knowledgement Infrastructure (CNKI) will be carried out from their inception until to December 30, 2020. Studies investigating the comparative effects between MBSR and control groups on psychological and physical outcomes will be documented. Data concerning studies, patient characteristics, and outcomes will be extracted. Methodological quality of each eligible randomized controlled trial (RCT) will be assessed individually by two investigators independently using criteria recommended in the Cochrane Handbook for Systematic Reviews of Interventions 5.1.0. Meanwhile, Newcastle-Ottawa Quality Assessment Scale (NOS) will be used to assess methodological quality of non-randomized studies. All statistical analyses will be performed with RevMan and STATA softwares.
Discussion: The role of MBSR in lung cancer patients has not yet been demonstrated. This systematic review and meta-analysis will further determine the effectiveness of MBSR on psychological and physical outcomes and QoL among lung cancer patients, which will provide golden references for developing psychological interventions in order to improve patient care and designing future studies to bridge the gap between research findings and clinical practice.
Trial Registration: We registered the protocol of this systematic review and meta-analysis in Open Science Framework (OSF) platform with a registration DOI of 10.17605/OSF.IO/MWVBQ (available from: https:// osf.io/mwvbq).
Comparable studies
Other systematic reviews and meta-analyses on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations | 2014 | Meta-analysis | n = 3,515 |
| Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects | 2009 | Systematic review and meta-analysis | |
| The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators | 2012 | Meta-analysis | n = 163 |
| Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission | 2016 | Meta-analysis of individual patient data from randomized controlled trials | n = 1,258 |
| Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials | 2011 | Systematic review |
Citations in the library
Cited by 3
- The Evaluation of the Adjunctive Therapeutic Value of Mindfulness-Based Stress Reduction Therapy for Patients With Nasopharyngeal Carcinoma Induced Moderate Depression. Actas Españolas de Psiquiatría May 1, 2025
- Innovating Mindfulness-Based Stress Reduction (MBSR) Delivery in Cancer Care: Enhancing Accessibility and Engagement Clinical Cancer Investigation Journal 2024
- The Impact of Mindfulness-Based Stress Reduction (MBSR) on Psychological Outcomes and Quality of Life in Patients With Lung Cancer: A Meta-Analysis Frontiers in Psychology June 28, 2022
Cites 8
- Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders American Journal of Psychiatry July 1, 1992
- Mindfulness-Based Cognitive Therapy for Depression: A New Approach to Preventing Relapse Psychotherapy Research March 1, 2003
- Mindfulness‐based interventions for psychological and physical health outcomes in cancer patients and survivors: A systematic review and meta‐analysis of randomized controlled trials Psycho-Oncology September 11, 2019
- Mindfulness-based stress reduction can alleviate cancer- related fatigue: A meta-analysis. Journal of Psychosomatic Research December 27, 2019
- Mindfulness-based stress reduction added to care as usual for lung cancer patients and/or their partners: A multicentre randomized controlled trial. Psycho-Oncology December 2017
and 3 more in the library