The Involvement of the Multiple Demand and Default Mode Networks in a Trial-by-Trial Cognitive Control.
Shinyoung Jung, Joo Yeon Kim, Suhyeon Jo, Suk Won Han
Brain Sciences August 26, 2023 DOI: 10.3390/brainsci13091247 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Neuroimaging study Peer reviewed |
|---|---|
| Sample size | 40 |
| Population | Human participants across two independent neuroimaging datasets |
| Topics | Default mode network |
| Keywords | Mvpa FMRI Multiple demand network Task coding |
| Key points | An attentional task produced positive MDN activity and DMN deactivation. Task features were decodable from fronto-parietal MDN regions, and also from DMN regions during rapid, trial-by-trial task-set reconfiguration. The authors suggest the two networks coordinate to support top-down cognitive control. |
Abstract
Adaptive behavior in the environment requires a high level of cognitive control to bias limited processing resources to behaviorally significant stimuli. Such control has been associated with a set of brain regions located in the fronto-parietal cortex (multiple demand network), whose activity was found to increase as the control demand for a task increases. In contrast, another set of regions, default mode network regions, were found to be deactivated during top-down processing of task stimuli. Despite this dissociation in their activation amplitudes, it is possible that activation patterns of these regions commonly encode specific task features. In two independent neuroimaging datasets, involving a total of 40 human samples, we found that the performance of an attentional task evoked positive activity of the MDN and deactivation of the DMN. Consistent with previous studies, task features could be decoded from the fronto-parietal cognitive regions. Importantly, the regions of the DMN also encoded task features when the task set had to be rapidly reconfigured in a transient, trial-by-trial manner, along with the MDN regions. These results suggest that the two separate brain networks ultimately co-ordinate for the effective establishment of top-down cognitive control.
Comparable studies
Other experimental studies on default mode network, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Functional connectivity of default mode network components: Correlation, anticorrelation, and causality Healthy subjects | 2008 | Observational study using resting-state fMRI and seed correlation analysis | |
| Patterns of Brain Activity Supporting Autobiographical Memory, Prospection, and Theory of Mind, and Their Relationship to the Default Mode Network Healthy subjects | 2009 | Experimental study using fMRI | |
| Dynamic reconfiguration of the default mode network during narrative comprehension Human subjects | 2016 | Experimental study | |
| Broadband Cortical Desynchronization Underlies the Human Psychedelic State Healthy human participants | 2013 | Experimental study | |
| The brain on art: intense aesthetic experience activates the default mode network Human observers | 2012 | Observational study with fMRI and behavioral analysis |
Citations in the library
Cites 5
- A default mode of brain function Proceedings of the National Academy of Sciences January 16, 2001
- Default mode network can support the level of detail in experience during active task states Proceedings of the National Academy of Sciences August 27, 2018
- Role of the Default Mode Network in Cognitive Transitions Cerebral Cortex June 21, 2018
- Default mode network connectivity during task execution Neuroimage July 26, 2015
- Functional connectivity in the resting brain: A network analysis of the default mode hypothesis Proceedings of the National Academy of Sciences December 27, 2002