Feasibility and acceptability of an online mindfulness-based group intervention for adults with tic disorders.
Hannah E. Reese, W Alan Brown, Berta J Summers, Jin Shin, Grace Wheeler, Sabine Wilhelm
Pilot and Feasibility Studies March 24, 2021 DOI: 10.1186/s40814-021-00818-y (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Feasibility study, single-cohort pre-post Randomized Qualitative Peer reviewed |
|---|---|
| Population | Adults with Tourette syndrome or persistent tic disorder |
| Intervention | Online mindfulness-based group intervention |
| Duration | 8-week intervention |
| Topics | Meditation |
| Keywords | Tourette syndrome Group treatment Online Tic disorder |
| Registration | NCT03525626 |
| Key findings | The online mindfulness-based group intervention was reported as feasible and acceptable, but home-practice adherence was lower than anticipated and improvements in mindfulness, tic severity, and tic-related impairment from baseline to posttreatment were only modest. The authors conclude the intervention should be modified to enhance adherence, engage the target mechanism, and optimize outcomes before a randomized controlled trial. |
Abstract
Background: Preliminary research suggests that a mindfulness-based treatment approach may be beneficial for adults with tic disorders. In the present study, we report on the feasibility, acceptability, safety, and symptomatic effect of a novel online mindfulness-based group intervention for adults with Tourette syndrome or persistent tic disorder. Data from this study will directly inform the conduct of a funded randomized controlled trial comparing the efficacy of this intervention to another active psychological intervention.
Methods: One cohort of adults with Tourette syndrome participated in an 8-week online mindfulness-based group intervention. Measures of feasibility, acceptability, and safety were administered throughout and at posttreatment. Self-reported measures of mindfulness and clinician-rated measures of tic severity and impairment were administered at baseline and posttreatment.
Results: Data on refusal, dropout rate, attendance, participant satisfaction, and safety suggest that this is a feasible and acceptable intervention. However, participant adherence to home practice was lower than anticipated. Mindfulness, tic severity, and tic-related impairment only modestly improved from baseline to posttreatment. Qualitative analysis of participant feedback revealed aspects of the intervention that were most helpful and also areas for improvement.
Conclusions: Data suggest that although this is a feasible and acceptable intervention, it should be modified to enhance participant adherence, more successfully engage the target mechanism, and optimize outcomes.
Trial Registration: Clinicaltrials.gov registration # NCT03525626 . Registered on 24 April 2018.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cited by 5
- Online mindfulness interventions in the care of people with physical and mental health conditions: a scoping review. BMJ Open July 18, 2025
- Development of a Coding Scheme for Interpersonal Mindfulness in Couple Dyads: Ratings of Observed Mindful Partnering. Journal of Marital and Family Therapy July 1, 2026
- Remote delivery of a mindfulness-based intervention for adults with tics: Protocol of a randomized controlled trial. Contemporary Clinical Trials January 13, 2026
- Mindfulness-Based Interventions for Tourette Syndrome: Current Status and Future Directions. Psychiatric Clinics of North America October 9, 2024
- Effects of a online brief modified mindfulness-based stress reduction therapy for anxiety among Chinese adults: A randomized clinical trial. Journal of Psychiatric Research May 2023
Cites 9
- Using Self-Report Assessment Methods to Explore Facets of Mindfulness Assessment January 27, 2006
- How Does Mindfulness Meditation Work? Proposing Mechanisms of Action From a Conceptual and Neural Perspective Perspectives on Psychological Science October 14, 2011
- What defines mindfulness-based programs? The warp and the weft Psychological Medicine December 29, 2016
- Home practice in Mindfulness-Based Cognitive Therapy and Mindfulness-Based Stress Reduction: A systematic review and meta-analysis of participants' mindfulness practice and its association with outcomes Behaviour Research and Therapy May 10, 2017
- Mindfulness-based interventions for psychiatric disorders: A systematic review and meta-analysis. Clinical Psychology Review February 1, 2018
and 4 more in the library