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Spurious prospective effects of mindfulness on anxiety and depressive symptoms: Reanalysis of a meta-analytic cross-lagged panel analysis

Kimmo Sorjonen, Bo Melin

preprint DOI: 10.31234/osf.io/c34w8 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Reanalysis of meta-analytic data
Topics Anxiety Meditation
Key points Argues that previously reported prospective effects of the mindfulness facets acting with awareness and non-reacting on later anxiety and depressive symptoms are spurious, because adjusted cross-lagged effects can arise from correlations with residuals and regression to the mean. Fitting competing models to the same meta-analytic data, the authors report no genuine prospective effects and caution against overinterpreting such adjusted estimates.

Abstract

A recent meta-analysis claimed decreasing prospective effects of acting with awareness and non-reacting, two facets of dispositional mindfulness, on subsequent anxiety and depressive symptoms. However, the meta-analytic cross-lagged effects were estimated while adjusting for a prior measurement of the outcome variable and it is known that such adjusted cross-lagged effects may be spurious due to correlations with residuals and regression to the mean. We fitted competing models on the same meta-analytic data and found prospective effects of the mindfulness facets on anxiety and depressive symptoms to be spurious. It is important for researchers to be aware of limitations of adjusted cross-lagged effects, meta-analytically estimated or not, in order not to overinterpret findings.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

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