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Effect of mindfulness meditation protocol in subjects with various psychometric characteristics at high altitude

Disha Bhanushali, Rahul Tyagi, Nitin Limaye (Rishi Nityapragya), Akshay Anand

Brain and Behavior May 1, 2020 DOI: 10.1002/brb3.1604 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Pre-post intervention study Peer reviewed
Sample size 48
Population Adults aged 20-65 years with no comorbidities, exposed to high altitude
Duration 4 days
Measures Happiness index, anxiety, mental well-being, information processing
Topics Meditation
Key points A four-day advanced meditation program at high altitude was associated with reduced Po2 and glucose and changes in happiness, anxiety, and mental well-being; participants with lowered Po2 showed improvements on anxiety, happiness, and information-processing scales. The authors report that those with a "Pitta" constitution changed on more parameters than "Vatta" or "Kapha" constitutions, and conclude the program confers biochemical and neuro-cognitive benefits.

Abstract

Abstract:

Introduction: Incidence of high altitude‐related sickness is increasing due to more number of people visiting the areas of high altitude which may result in life‐threatening conditions including acute mountain sickness (AMS), high altitude pulmonary edema (HAPE), high altitude cerebral edema (HACE), and High‐altitude pulmonary hypertension (HAPH). We hypothesized that an advanced yoga regimen may be beneficial in dealing with the physiology of acclimatization.

Methods: Anthropometric, Biochemical, and Psychological assessments were carried out in 48 participants before and after the advance meditation program (AMP) in the experimental group. Individuals with an age range of 20–65 years with no comorbidities were included in the study. Participants were exposed to AMP for 4 days. All assessments were carried out at the baseline and after the course. Prakriti was constituted for all participants using a standard questionnaire. The study was carried out after obtaining the written informed consent as per the guidelines outlined by the Institute Ethics Committee.

Results: Po2 and glucose levels were found significantly reduced along with changes in the Happiness index, anxiety, and mental well‐being. However, participants with lowered Po2, after 4 days of mindfulness intervention, showed a positive outcome measured by the established scales of anxiety, happiness, and information processing. Psychometric or Prakriti wise analysis revealed that subject with “ Pitta ” constitution exposed to high altitude and advance meditation showed changes in more parameters than “ Vatta ” or “ Kapha ” Constitution.

Conclusions: Advance meditation in the high altitude zone confers biochemical and neuro‐cognitive benefits. Molecular studies may require to understand the role of hypoxic condition in improving the disease state.

Comparable studies

Other non-randomized and open-label trials on meditation, most cited first.

Study Year Design Participants
Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients 2003 Pre-post intervention study n = 59
Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample 2010 Pre-post intervention study
Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students 2003 Prospective nonrandomized cohort-controlled study n = 302
Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls 2011 Controlled trial with wait-list control group n = 60
The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents 2011 Within-group waitlist controlled trial n = 22

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