Effect of short-term mindfulness-based stress reduction on sleep quality in male patients with alcohol use disorder.
Yongmei Wang, Cuiping Chen, Lina Gu, Yi Zhai, Yanhong Sun, Guoqing Gao, Yayun Xu, Liangjun Pang, Lianyin Xu
Frontiers in Psychiatry 2023 DOI: 10.3389/fpsyt.2023.928940 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 91 |
| Population | Male patients with alcohol use disorder after 2 weeks of routine withdrawal therapy |
| Interventions | Mindfulness-based stress reduction (MBSR) supportive therapy |
| Duration | 2-week intervention, measured at baseline and 2 weeks after treatment |
| Measures | Cardiopulmonary coupling (CPC), total sleep time, stable sleep time, unstable sleep time, rapid eye movement (REM) sleep time, wake-up time, stable sleep latency, sleep efficiency, apnea index |
| Topics | Addiction Meditation |
| Keywords | Apnea index Cardiopulmonary coupling Mindfulness-based stress reduction Sleep quality |
| Key findings | Adding 2 weeks of MBSR to supportive therapy significantly increased total sleep time and stable sleep time and significantly decreased the average apnea index compared with supportive therapy alone in men with alcohol use disorder after withdrawal. The authors suggest short-term MBSR may improve sleep quality and could be an alternative to hypnotics for post-withdrawal sleep disturbance. |
Abstract
Sleep disturbance is one of the most prominent complaints of patients with alcohol use disorder (AUD), with more than 70% of patients with AUD reporting an inability to resolve sleep problems during abstinence. Mindfulness-based stress reduction (MBSR) has been shown to improve sleep quality and as an alternative therapy to hypnotics for sleep disorders. The aim of the present study was to evaluate the effect of short-term MBSR on sleep quality in male patients with AUD after withdrawal. A total of 91 male patients with AUD after 2 weeks of routine withdrawal therapy were randomly divided into two groups using a coin toss: the treatment group (n = 50) and the control group (n = 41). The control group was received supportive therapy, and the intervention group added with MBSR for 2 weeks on the basis of supportive therapy. Objective sleep quality was measured at baseline and 2 weeks after treatment using the cardiopulmonary coupling (CPC). Indicators related to sleep quality include total sleep time, stable sleep time, unstable sleep time, rapid eye movement (REM) sleep time, wake-up time, stable sleep latency, sleep efficiency, and apnea index. These indicators were compared by an analysis of covariance (ANCOVA) between the two groups, controlling for individual differences in the respective measures at baseline. The results showed that there were no significant differences in the age [t (89) = -0.541, P = 0.590), BMI [t (89) = -0.925, P = 0.357], educational status [t (89) = 1.802, P = 0.076], years of drinking [t (89) = -0.472, P = 0.638), daily intake [t (89) = 0.892, P = 0.376], types of alcohol [χ2 (1) = 0.071, P = 0.789], scores of CIWA-AR [t (89) = 0.595, P = 0.554], scores of SDS [t (89) = -1.151, P = 0.253), or scores of SAS [t (89) = -1.209, P = 0.230] between the two groups. Moreover, compared with the control group, the total sleep time [F (1.88) = 4.788, P = 0.031) and stable sleep time [F (1.88) = 6.975, P = 0.010] were significantly increased in the treatment group. Furthermore, the average apnea index in the patients who received MBSR was significantly decreased than in the control group [F (1.88) = 5.284, P = 0.024]. These results suggest that short-term MBSR could improve sleep quality and may serve as an alternative treatment to hypnotics for sleep disturbance in patients with AUD after withdrawal.
Comparable studies
Other randomized controlled trials on addiction, most cited first.
Citations in the library
Cited by 2
- A short-term mindfulness and auricular acupressure program for preoperative sleep fragmentation in patients with spinal metastases: a retrospective quasi-experimental study. Frontiers in Psychiatry 2026
- Long-Term Effects of Mindfulness-Based Stress Reduction on Sleep Quality in Family Caregivers of People With Alzheimer's Disease: The Mediating Role of Anxiety. Clinical Gerontologist 2026
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