The effect of mindfulness on decision-making, inhibitory control, and impulsivity of substance use disorder in-treatment patients: A randomized clinical trial.
Ana Paula Gonçalves Donate, Elizeu Coutinho De Macedo, Andre Bedendo, Itamar Félix Júnior, Giovanna Gonçalves Gallo, Emérita Sátiro Opaleye, Ana Regina Noto
PLoS One 2023 DOI: 10.1371/journal.pone.0293502 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Randomized controlled trial Peer reviewed |
|---|---|
| Sample size | 122 |
| Population | Individuals with substance use disorders in a therapeutic community in Brazil |
| Interventions | Mindfulness-Based Relapse Prevention (MBRP) treatment as usual (TAU) |
| Duration | 8-week intervention |
| Measures | Iowa Gambling Task, UPPS-P Scale, Stroop Color-Word Test |
| Topics | Addiction Meditation |
| Key findings | Adding Mindfulness-Based Relapse Prevention to treatment as usual improved general decision-making scores on the Iowa Gambling Task compared with treatment as usual alone. No significant effects were found for impulsivity dimensions or inhibitory control. |
Abstract
This study aimed to investigate the effects of Mindfulness-Based Relapse Prevention (MBRP) in decision-making, inhibitory control and impulsivity compared to Treatment as Usual (TAU) for individuals with Substance Use Disorders (SUD's) in Brazil. A randomized clinical trial was conducted with participants from a therapeutic community (n = 122). Decision-making (Iowa Gambling Task), impulsivity dimensions (UPPS-P Scale), and inhibitory control (Stroop Color-Word Test) were assessed before and after the MBRP 8-week intervention. GLM Multivariate analysis was used to evaluate the effects of MBRP on different impulsivity measures. The results showed that MBRP+TAU improved the general decision-making score (p = 0,008) compared to TAU. However, no significant effects were found in impulsivity dimensions and inhibitory control in individuals with SUDs in the therapeutic community. This study found improvement in decision-making in the total IGT score; however, no effect for self-reported impulsivity and inhibitory control among middle-aged patients after an 8-weeks intervention of MBRP protocol in an inpatient setting. It adds information to the subject, with implications and possible directions to be followed by the next clinical trials with patients with SUDs in treatment. Trial registration: EnsaiosClinicos.gov.br: RBR-6c9njc.
Comparable studies
Other randomized controlled trials on addiction, most cited first.
Citations in the library
Cites 7
- The Effect of Mindfulness Meditation on Impulsivity and its Neurobiological Correlates in Healthy Adults Scientific Reports August 19, 2019
- Mindfulness-based interventions in inpatient treatment for Substance Use Disorders: A systematic review. Addictive Behaviors Reports November 11, 2022
- Development of a mindfulness-based treatment for smoking cessation and the modification of alcohol use: A protocol for a randomized controlled trial and pilot study findings. Contemporary Clinical Trials November 14, 2020
- The (Lack of) Replication of Self-Reported Mindfulness as a Mechanism of Change in Mindfulness-Based Relapse Prevention for Substance Use Disorders. Mindfulness April 2019
- [Mindfulness-based-relapse prevention (MBRP): Evaluation of the impact of a group of Mindfulness Therapy in alcohol relapse prevention for alcohol use disorders]. L'Encephale December 1, 2015
and 2 more in the library