Mindfulness-enhanced internet-based cognitive behavioural therapy for anxiety and depression: Outcomes in routine care.
Claudia Hurwitz, Christine T Shiner, Maria J Sharrock, Michael Millard, Alison Mahoney
Journal of Affective Disorders August 23, 2023 DOI: 10.1016/j.jad.2023.08.073 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational cohort Peer reviewed |
|---|---|
| Sample size | 2,187 |
| Population | Adults in the general Australian community who commenced an online mindfulness-enhanced CBT program (mean age 39 ± 14 years, 68% female) |
| Duration | Six sequential lessons to be completed within 90 days; measures at pre-, mid-, and post-treatment |
| Topics | Anxiety Depression Meditation |
| Keywords | Humans Adult Middle aged Australia Female Cognitive behavioral therapy Effectiveness Internet intervention Icbt |
| Key findings | The mindfulness-enhanced internet-based CBT program was associated with medium to large reductions in generalised anxiety (g = 0.80), depression (g = 0.74), and psychological distress (g = 0.97) from pre- to post-treatment. About 30% of participants completed all six lessons. The authors conclude the program supports effectiveness for anxiety and depression symptoms in routine care, while noting the lack of a comparator and longer-term follow-up. |
Abstract
Background: Clinical trials support the efficacy of mindfulness-enhanced, internet-based cognitive behavioural therapies (CBT) in reducing anxiety and depression symptom severity. However, it is unclear how effective these interventions are when delivered in routine clinical care settings. This study investigated the utilisation and treatment outcomes of an online mindfulness-enhanced CBT program in the general Australian community.
Methods: Over a one-year study period, 2187 adults commenced the online mindfulness-enhanced CBT program. The program consisted of six sequential lessons to be completed within 90 days.
Participants: (mean age= 39 ± 14 years, 68 % female) completed measures of symptom severity for anxiety, depression, and psychological distress at pre-, mid- and post-treatment. Treatment effects were assessed via intention-to-treat linear mixed models with Hedges' g effect size calculations.
Results: From pre- to post-treatment, the mindfulness-enhanced CBT program was associated with medium and large effect sized reductions in generalised anxiety symptom severity (g = 0.80, 95%CI: 0.74-0.86), depression symptom severity (g = 0.74, 95%CI: 0.68-0.80), and psychological distress (g = 0.97, 95%CI: 0.90-1.03). Program adherence was modest with approximately 30 % of participants completing all six lessons of the program.
Limitations: This study is limited by its lack of a comparator condition, longer-term follow-up, and assessment of the reasons for participant non-adherence. The relative acceptability and effectiveness of mindfulness versus CBT components was not examined.
Conclusion: This study supports the effectiveness of mindfulness-enhanced iCBT for symptoms of anxiety and depression when delivered in a routine care setting under the supervision of community health care practitioners.
Comparable studies
Other observational and cohort studies on anxiety, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders Patients with generalized anxiety disorder or panic disorder with or without agoraphobia | 1992 | Observational cohort | n = 22 |
| Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder | 2015 | Observational study | |
| Patterning of Cognitive and Somatic Processes in the Self-Regulation of Anxiety: Effects of Meditation versus Exercise Regular practitioners of physical exercise or meditation | 1978 | Retrospective study | n = 77 |
| Dynamic coupling of whole-brain neuronal and neurotransmitter systems Healthy humans | 2020 | Observational study | |
| Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults | 2015 | Observational cohort | n = 135,095 |
Citations in the library
Cited by 2
- Predicting social adjustment based on mindfulness and emotion regulation in university students through panel data model Research and Development in Medical Education September 8, 2024
- Can cognitive behavioral additions improve the efficacy of self-help mindfulness intervention for depression and anxiety ?: A randomized controlled trial. Behaviour Research and Therapy March 15, 2026