The Effects of Mindfulness on Glycemic Control in People with Diabetes: An Overview of Systematic Reviews and Meta-Analyses.
Hidetaka Hamasaki
Medicines September 7, 2023 DOI: 10.3390/medicines10090053 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Randomized Peer reviewed |
|---|---|
| Population | People with diabetes, particularly type 2 diabetes |
| Intervention | Mindfulness interventions |
| Measures | hemoglobin A1c (HbA1c) |
| Topics | Meditation |
| Keywords | Diabetes Glycemic control Randomized controlled trial Systematic review |
| Key findings | Four of five systematic reviews and meta-analyses of randomized controlled trials reported that mindfulness interventions significantly reduced HbA1c by approximately 0.3% and reduced stress, depression, and anxiety in people with diabetes. The author concludes that mindfulness is effective for glycemic control in type 2 diabetes, but notes that inadequate reporting of participant characteristics and heterogeneity in intervention methods leave the overall quality of evidence uncertain. |
Abstract
Background: Previous research has demonstrated the effectiveness of mindfulness interventions in improving glycemic control. By enhancing attention control, emotion regulation, and self-awareness, mindfulness shows promise in managing the lifestyle factors associated with cardiovascular disease risk. However, the impact of mindfulness on glycemic control in people with diabetes remains unclear. This overview aims to summarize the current evidence of the impact of mindfulness interventions on glycemic control in people with diabetes and propose suggestions for future research.
Methods: The author searched electronic databases (PubMed/MEDLINE, Embase, and Cochrane Library) to identify relevant systematic reviews and meta-analyses. The current evidence regarding the effects of mindfulness on glycemic control in people with diabetes was summarized.
Results: This review evaluated a total of five systematic reviews and meta-analyses of randomized controlled trials (RCTs). Mindfulness interventions show potential for improving glycemic control as measured by hemoglobin A1c (HbA1c) levels, as well as reducing stress, depression, and anxiety in people with diabetes. Four out of five systematic reviews and meta-analyses reported a significant reduction in HbA1c levels by approximately 0.3%. However, the available studies lacked adequate description of key characteristics of study subjects, such as body mass index, medication, and disease conditions, which are essential for assessing the impact of mindfulness on glycemic control. Moreover, there was significant heterogeneity in the intervention methods employed across the included RCTs.
Conclusions: Mindfulness interventions are effective in improving glycemic control in people with type 2 diabetes. However, the overall quality of the reviewed studies raises uncertainty regarding the effectiveness of mindfulness as a treatment for people with diabetes. Further research is necessary to elucidate the biological effects of mindfulness on physiological, neurological, and endocrinological functions in humans.
Comparable studies
Other narrative reviews on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness training as a clinical intervention: A conceptual and empirical review. Clinical populations | 2003 | Review | |
| Mindfulness: Theoretical Foundations and Evidence for its Salutary Effects | 2007 | Review | |
| Mindfulness Interventions | 2016 | Review | |
| Mind the Hype: A Critical Evaluation and Prescriptive Agenda for Research on Mindfulness and Meditation | 2017 | Review | |
| Mindfulness and acceptance: expanding the cognitive-behavioral tradition | 2005 | Review |
Citations in the library
Cited by 3
- Effect of mindfulness-based interventions on anxiety, depression, and stress in patients with coronary artery disease: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Psychology 2024
- Mindfulness-Based Stress Reduction Program to Improve Well-Being and Health in Healthcare Professionals. Journal of Clinical Medicine October 28, 2025
- Mindfulness-Based Interventions and the Hypothalamic-Pituitary-Adrenal Axis: A Systematic Review. Neurology International November 20, 2024
Cites 14
- Mindfulness-based interventions: an overall review British Medical Bulletin April 21, 2021
- Effects of Meditation Intervention on Self-management in Adult Patients With Type 2 Diabetes: A Systematic Literature Review and Meta-analysis. The Journal of cardiovascular nursing February 3, 2023
- Effects of stress and mindfulness on epigenetics. Vitamins and hormones 2023
- Examining the interrelationships between mindfulness‐based interventions, depression, inflammation, and cancer survival Ca June 16, 2022
- Evaluation of the effects of 12 weeks mindfulness-based stress reduction on glycemic control and mental health indices in women with diabetes mellitus type 2 Advanced Biomedical Research November 4, 2020
and 9 more in the library