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D‐cycloserine treatment after ketamine infusions did not improve symptoms of depression

The Brown University Psychopharmacology Update December 1, 2019 DOI: 10.1002/pu.30506 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics News report Peer reviewed
Population Patients with depression who had responded to doses of ketamine
Intervention ketamine
Duration 6 weeks
Topics Depression Esketamine Ketamine
Key points Six weeks of D-cycloserine did not improve depressive symptoms compared with placebo in patients who had responded to ketamine, but it did maintain ketamine's anti-suicidal effects.

Abstract

Six weeks of D‐cycloserine treatment for patients with depression who had responded to doses of ketamine did not improve depressive symptoms compared with placebo, a study has found. D‐cycloserine was found to maintain the anti‐suicidal effects of ketamine, however.