Ketamine in Clinical Practice: State of The Art Usage
January 23, 2019 DOI: 10.64239/pi-vl14 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review |
|---|---|
| Intervention | Ketamine |
| Topics | Esketamine Ketamine |
| Key findings | Ketamine produces rapid antidepressant and anti-suicidal effects in depression, but these are transient and accompanied by safety concerns such as dissociation, psychotomimetic effects, hemodynamic changes, and abuse potential. The authors argue that ketamine's therapeutic role in psychiatric practice remains promising but requires careful monitoring and further research to establish long-term safety and optimal use. |
Abstract
Define the therapeutic role of ketamine in depression and suicidal ideation. Outline the safety concerns related to the use of ketamine in psychiatric practice.
Comparable studies
Other narrative reviews on ketamine, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms | 2018 | Review | |
| Mechanisms of Ketamine Action as an Antidepressant | 2018 | Review | |
| Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation Adults with treatment-resistant depression | 2021 | Review | |
| Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings) | 2013 | Review | |
| A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders | 2017 | Review and consensus statement |