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Presentation of Psychosis Subsequent to Penile Injection of MDMA in a 60-year-old Patient-A Case Report

Ana Lilian Reyes, Brittany Michael, Tessy Korah

preprint DOI: 10.21203/rs.3.rs-268881/v1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report
Sample size 1
Population A 60-year-old Caucasian male with a history of polysubstance use
Interventions Intramuscular ceftriaxone oral minocycline
Duration Three days of intramuscular ceftriaxone and six days of oral minocycline
Topics MDMA
Key findings The authors report a case in which a man who injected MDMA into a penile dorsal vein developed a penile abscess and psychotic symptoms, and they argue that clinicians should obtain thorough histories and consider uncommon routes of drug administration in patients presenting with intravenous drug use.

Abstract

Abstract The street drug Molly, the crystal or powder form of MDMA (3,4-methylenedioxymethylamphetamine) is commonly ingested via oral or pulmonary routes. Intravenous administration of MDMA is rare and here we report a case of penile dorsal vein injection of Molly, development of penile abscess, and subsequent psychotic symptoms in a patient with a history of polysubstance use. A 60-year-old Caucasian male was presented to the psychiatric hospital with a chief complaint of hallucinations and homicidal and suicidal ideation following reported use of MDMA. Three days into his hospitalization, he began to experience sever penile pain and upon interviewing disclosed penile injection of MDMA prior to admission. Examination revealed a 1.5 X 0.7 cm abscess with minimal drainage and surrounding erythema on the body of the penis. The treatment course consisted of three days of intramuscular ceftriaxone and six days of oral Minocycline. In this case report, we discuss the challenges and importance of obtaining a thorough history for patients presenting with IV drug use as well as considering uncommon routes of administration.

Comparable studies

Other case reports and case series on MDMA, most cited first.

Study Year Design Participants
'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use 1987 Case series n = 5
Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... 1996 Case series n = 7
'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA 1987 Case series n = 5
A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... 1998 Case study n = 2
Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... 1994 Case series n = 13

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