Targeting Phantom Pain with Psilocybin: Toward Integration with Adaptive Sensory Technologies
ACS Medicinal Chemistry Letters April 10, 2025 DOI: 10.1021/acsmedchemlett.5c00182 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Interventions | Psilocybin Adaptive sensory environments |
| Topics | Psilocybin |
| Keywords | Sensory system Phantom limb Imaging phantom |
| Key findings | Psilocybin reduces phantom and residual limb pain by a clinically meaningful amount. |
Abstract
Psilocybin demonstrates a clinically meaningful reduction in phantom and residual limb pain. Adaptive sensory environments (ASEs) separately offer biosensor-guided modulation of psychological states during psychoactive therapy. This Patent Highlight explores the pharmacological findings of a psilocybin trial and discusses future integration with ASE systems to precision and scale psychedelic-assisted interventions.
Comparable studies
Other narrative reviews on psilocybin, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function. General population | 2019 | Integrative review | |
| The pharmacology of psilocybin | 2002 | Review | |
| Serotonin research: contributions to understanding psychoses | 2008 | Review | |
| Psychedelics, Meditation, and Self-Consciousness | 2018 | Review | |
| The abuse potential of medical psilocybin according to the 8 factors of the Controlled Substances Act | 2018 | Review |
Citations in the library
Cites 2
- Psychedelic-Induced Neural Plasticity: A Comprehensive Review and a Discussion of Clinical Implications. Brain Sciences January 25, 2025
- Psychedelics and connectedness to natural and social worlds: An examination of the evidence and a proposed conceptual framework. Current Opinion in Psychology April 1, 2025