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Mindfulness Apps to Improve Depression Severity and Family Management in Parents of Children With Medical Complexity: A Pilot Study.

Cara Gallegos, V. Toly, Matthew Bailey

Journal for Specialists in Pediatric Nursing November 30, 2025 DOI: 10.1111/jspn.70011 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Single-arm intervention pilot study Peer reviewed
Sample size 32
Population Parents of children with medical complexity
Intervention Mindfulness mobile application
Dose 10-15 minutes, 4 days a week
Duration 4 weeks
Measures Patient Health Questionnaire-9, Family Management Measure
Topics Depression Meditation
Key points Among 32 parents of children with medical complexity, a four-week mindfulness app intervention was feasible and acceptable, with most participants rating it easy to use and recommending it. Depression severity and family management scores improved significantly from baseline to four weeks. Time spent using the app correlated strongly with lower depression severity, while days used per week did not.

Abstract

Purpose: Parents of children with medical complexity (CMC) frequently experience challenges with family management and depression. The purpose of the study was to provide preliminary feasibility, usage, acceptability, and efficacy data following a trial of mindfulness app use in parents of a CMC.

Design: AND METHODS In this single-arm intervention pilot study, parents were asked to use a mindfulness mobile application (app) for 10-15 min, 4 days a week. Depression severity and family management were measured using the Patient Health Questionnaire-9 and Family Management Measure, respectively, at baseline and 4 weeks later.

Results: A total of 32 parents consented to participate; 28 parents completed all surveys. Self-reported usage data indicate that 8 parents (32%) used the app 4 days a week and 12 parents (50%) used it for at least 10 min/session. The majority rated the app easy to use and would recommend it (n = 26; 92.8%). There was a statistically significant improvement in depression severity and family management scores following app use. Time spent using the app had a strong negative correlation with depression severity scores (p <0.01), however, the number of days used per week of use was not statistically significant. PRACTICE IMPLICATIONS Parents of a CMC are at risk for depression and family management issues. Timely identification of parental mental health is important so interventions can be provided. This pilot study provides promising, preliminary information regarding the feasibility, acceptability, and efficacy of a mindfulness app intervention.

Comparable studies

Other non-randomized and open-label trials on depression, most cited first.

Study Year Design Participants
Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. Patients with moderate-to-severe, unipolar, treatment-resistant major depression 2016 Open-label feasibility trial n = 12
Psilocybin with psychological support for treatment-resistant depression: six-month follow-up. Patients with severe, unipolar, treatment-resistant major depression 2017 Open-label trial n = 20
Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression Patients with treatment-resistant depression 2018 Clinical trial n = 20
Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder Subjects with DSM-IV-diagnosed treatment-resistant major depressive disorder 2010 Open-label trial n = 33
Antidepressant Effects of a Single Dose of Ayahuasca in Patients With Recurrent Depression Patients with recurrent depression 2015 Open-label trial n = 17

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