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Feasibility of Modified Mindfulness Training Program on Antenatal Depression and Perceived Stress Among Expected Mothers with Male Child Preference

. Badil, Najma Naz, Dildar Muhammad, Khalid Rehman -

preprint DOI: 10.20944/preprints202502.0316.v1 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Feasibility trial Qualitative
Population Pregnant women with antenatal depression and perceived stress who preferred a male child, at a public sector tertiary care hospital in Karachi, Pakistan
Intervention Modified mindfulness training program
Topics Depression Meditation
Key findings The authors report that a culturally adapted mindfulness training program significantly reduced antenatal depression and perceived stress scores over time in pregnant women with a male-child preference, with the largest declines occurring between the first and second assessment points, and they conclude the program is culturally suitable and contextually relevant for Pakistan.

Abstract

Background and

Objectives: Antenatal depression and perceived stress are prevalent mental health challenges in pregnant women, associated with male-child preference. The study aimed to assess the feasibility of a modified mindfulness training program on antenatal depression and perceived stress levels among expected mothers with male child preference at a public sector tertiary care hospital in Karachi, Pakistan.

Materials and Methods: The present feasibility trial was conducted among expected mothers having antenatal depression and perceived stress with a male child's preference by using the ADAPT-ITT framework. Need assessment and experiences of the new target population were carried out through an exploratory, descriptive qualitative study. In-depth interviews were conducted using a semi-structured interview guide and analysed using a thematic analysis process. A repeated measures MANOVA was employed to investigate the effect of time on antenatal depression and perceived stress scores in the feasibility of the intervention.

Results: Five major themes emerged from qualitative data. Significant influence of time was established on antenatal depression scores and a perceived score of F (2, 326) = 21.244, p < .001 and F (2, 326) = 310.748, p < 0.001 respectively. Antenatal depression scores significantly decreased from T1 to T2, mean difference = 4.00, p < .001, and slightly significant decline from T2 to T3, mean difference = 1.167, p = 0.001. Perceived stress scores significantly reduced from T1 to T2, mean difference = 10.214, p < .001, and a minor but significant decline from T2 to T3, mean difference = 0.333, p = 0.043.

Conclusion: The study concluded the modified mindful training program is a culturally suitable, contextually relevant intervention in Pakistan's context and it significantly reduced antenatal depression and perceived stress in expected mothers.

Comparable studies

Other non-randomized and open-label trials on depression, most cited first.

Study Year Design Participants
Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study. Patients with moderate-to-severe, unipolar, treatment-resistant major depression 2016 Open-label feasibility trial n = 12
Psilocybin with psychological support for treatment-resistant depression: six-month follow-up. Patients with severe, unipolar, treatment-resistant major depression 2017 Open-label trial n = 20
Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression Patients with treatment-resistant depression 2018 Clinical trial n = 20
Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder Subjects with DSM-IV-diagnosed treatment-resistant major depressive disorder 2010 Open-label trial n = 33
Antidepressant Effects of a Single Dose of Ayahuasca in Patients With Recurrent Depression Patients with recurrent depression 2015 Open-label trial n = 17

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