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Cannabis and psychosis: from the population attributable fraction to the importance of gender differences

C. Hjorthøj

European Psychiatry April 1, 2025 DOI: 10.1192/j.eurpsy.2025.45 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Peer reviewed
Topics Cannabis
Key points Argues that if the long-observed consistent association between cannabis and psychotic disorders such as schizophrenia is causal, cannabis may be the single most important preventable risk factor for schizophrenia identified to date. The presentation reviews Danish data on cannabis-induced psychosis and epidemiological associations, including trends in the population attributable risk fraction and gender differences.

Abstract

AbstractI will present data from a range of Danish studies on both cannabis-induced psychosis and Danish epidemiological studies on the association between cannabis and psychotic disorders such as schizophrenia. A deeper understanding of these associations is important. If the consistent association that we have observed for many decades is indeed causal, then cannabis is perhaps the single most important preventable risk factor for schizophrenia that we have identified to date. The development over time of the population attributable risk fraction, gender differences, and other novel areas will be covered in the presentation.Disclosure of InterestNone Declared