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Novel Non-hallucinogenic Neurite Growth Compounds as 5‑HT2A Agonists for Treating Stress-Related Disorders, Namely Depression, Anxiety, and PTSD.

ACS Medicinal Chemistry Letters July 30, 2025 DOI: 10.1021/acsmedchemlett.5c00440 (opens in new tab)

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AI-extracted from the abstract
Characteristics Peer reviewed
Topics Anxiety Depression PTSD

Abstract

Provided herein are novel non-hallucinogenic neurite growth compounds as 5-HT2A agonists, pharmaceutical compositions, use of such compounds in treating stress-related disorders, namely depression, anxiety, and post-traumatic stress disorder (PTSD), and processes for preparing such compounds.

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