Fatal poisoning by MDMA (ecstasy) and MDEA: a case report.
V Fineschi, A Masti
International Journal of Legal Medicine 1996 DOI: 10.1007/bf01369826 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Topics | MDMA |
| Keywords | Lung Kidney tubules Capillaries Humans Myoglobinuria Pulmonary embolism Poisoning N-methyl-3,4-methylenedioxyamphetamine Hallucinogens Designer drugs Fluorescent antibody technique Gas chromatography-mass spectrometry Drug overdose |
| Key findings | The authors report the first observation in Italy of lethal recreational use of MDMA and MDEA, with toxicological and histopathological documentation. They highlight disseminated intravascular coagulation, rarely reported before, and argue for its inclusion in the toxic syndrome framework to better define forensic diagnostic criteria. |
Abstract
The first observation of lethal recreational use of MDMA (ecstasy) and MDEA in Italy is reported, together with extensive toxicological and histopathological documentation. Findings such as disseminated intravascular coagulation, rarely reported before, are colocated in the framework of the toxic syndrome for a better definition of criteria for forensic diagnosis.
Comparable studies
Other case reports and case series on MDMA, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA Individuals whose deaths were associated with MDMA or MDEA use | 1987 | Case series | n = 5 |
| Pathology of deaths associated with "ecstasy" and "eve" misuse. Young white men aged 20 to 25 who died after using ring-substituted amphetamines (MDMA... | 1996 | Case series | n = 7 |
| 'Eve' and 'Ecstasy' Individuals who died after using MDMA or MDEA | 1987 | Case series | n = 5 |
| A Method of Conducting Therapeutic Sessions with MDMA Clients with clear therapeutic purpose, excluding those with serious functional... | 1998 | Case study | n = 2 |
| Diversity of Psychopathology Associated with use of 3,4-Methylenedioxymethamphetamine (‘Ecstasy’) Psychiatric patients presenting between 1990 and 1992 whose symptoms developed in the... | 1994 | Case series | n = 13 |
Citations in the library
Cited by 10
- Death following ingestion of MDMA (ecstasy) and moclobemide Addiction February 20, 2003
- Ecstasy (MDMA) Deaths in New York City: A Case Series and Review of the Literature Journal of Forensic Sciences 2002
- Fatal multi-organ failure after suicidal overdose with MDMA, `Ecstasy': case report and review of the literature Human & Experimental Toxicology February 1, 1999
- Distribution Study of 3,4-Methylenedioxymethamphetamine and 3,4-Methylenedioxyamphetamine in a Fatal Overdose Journal of Analytical Toxicology March 1, 2002
- The Neuropsychopharmacology and Toxicology of 3,4‐methylenedioxy‐N‐ethyl‐amphetamine (MDEA) CNS Drug Reviews June 1, 2004
and 5 more in the library
Cites 9
- Subjective Reports of the Effects of MDMA in a Clinical Setting Journal of Psychoactive Drugs October 1, 1986
- 'Eve' and 'Ecstasy'. A report of five deaths associated with the use of MDEA and MDMA JAMA March 27, 1987
- The Psychological and Physiological Effects of MDMA on Normal Volunteers Journal of Psychoactive Drugs October 1, 1986
- 'Eve' and 'Ecstasy' JAMA March 27, 1987
- Multiple Severe Complications From Recreational Ingestion of MDMA ('Ecstasy') JAMA August 14, 1987
and 4 more in the library