The chronic cerebral effects of cannabis use. I. Methodological issues and neurological findings.
R C Wert, M L Raulin
International Journal of the Addictions June 1986 DOI: 10.3109/10826088609027381 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Cannabis |
| Key findings | Concludes that available research provides no evidence that marijuana produces gross structural cerebral changes and little evidence that it leads to functional impairment, although subtle impairment cannot be ruled out. The author emphasizes methodological problems in the existing research. |
Abstract
This paper examines the research evidence relating sustained use of marijuana to chronic cerebral impairment. Evidence from both American and cross-cultural studies is reviewed, with a particular emphasis on methodological problems in the research. The focus of this paper is on neurological findings while another paper focuses on neuropsychological findings. On the basis of available research, it was concluded that there is no evidence that marijuana produces gross structural cerebral changes and little evidence that it leads to functional impairment, although subtle impairment cannot be ruled out.
Comparable studies
Other narrative reviews on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Causal association between cannabis and psychosis: examination of the evidence | 2004 | Review | |
| Cannabis sativa: A comprehensive ethnopharmacological review of a medicinal plant with a long history. General (historical and pharmacological review) | 2018 | Review | |
| Psychiatric effects of cannabis | 2001 | Review | |
| Beyond THC: The New Generation of Cannabinoid Designer Drugs | 2011 | Review | |
| Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug | 2006 | Review |
Citations in the library
Cited by 3
- The effect of cannabis on the brain: can it cause brain anomalies that lead to increased risk for schizophrenia? Current Opinion in Psychiatry March 1, 2008
- Neurotoxicology of cannabis and THC: a review of chronic exposure studies in animals. Pharmacology, Biochemistry, and Behavior November 1991
- Cannabis and psychosis. Is there epidemiological evidence for an association? The British Journal of Psychiatry July 1, 1990
Cites 4
- Neuropsychological Assessment of Undergraduate Marihuana and LSD Users Archives of General Psychiatry November 1, 1974
- Cognition and Long-Term Use of Ganja (Cannabis) Science July 24, 1981
- Multiple drug abuse involving nonopiate, nonalcoholic substances. II. Physical damage, long-term psychological effects and treatment approaches and success. International Journal of the Addictions April 1981
- Some psychological correlates of long-term heavy cannabis users. The British Journal of Psychiatry May 1978