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Effectiveness of mindfulness meditation on balance, cognitive functions, quality of life, and falls prevention in Parkinson's disease: A systematic review.

Purani Bogahawatta, Ashan Wijekoon, Thameesha Harini, Asha H Wettasinghe

Neuropsychological rehabilitation September 7, 2026 DOI: 10.1080/09602011.2026.2725697 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Randomized Peer reviewed
Topics Anxiety Depression Meditation
Keywords Parkinson’s disease Falls prevention Mobility
Key findings Mindfulness meditation improved anxiety, depression, and quality of life in Parkinson's disease, but evidence for motor, physical, and cognitive outcomes was inconsistent or limited. Falls-related outcomes were not evaluated.

Abstract

Scientific interest in mindfulness meditation as complementary therapy for Parkinson's disease (PD) has grown significantly. This systematic review examined mindfulness meditation effects on PD motor, cognitive, falls-related (fear of falling (FoF), freezing of gait (FoG), falls prevention), psychological (anxiety and depression), physical (balance, mobility, gait velocity), and quality of life (QoL) outcomes. A comprehensive search of PubMed, Web of Science, PEDro, Scopus, Cochrane Library, and ClinicalTrials.gov was conducted from database inception to May 2026. Data extraction and risk of bias assessment were performed independently by two reviewers. Fourteen studies met inclusion criteria: nine randomized controlled trials and five pre-post design studies. Following mindfulness meditation interventions: (1) Robust improvements were observed in anxiety symptoms; (2) Significant improvements were reported in depression and QoL; (3) Motor symptom improvements were inconsistent with limited evidence; (4) Findings on physical function outcomes, including balance and mobility, provided limited evidence of benefit, while one study demonstrated reduced gait speed; (5) Cognitive function improvements were mixed with benefits in specific domains but inconsistent general results; (6) Falls, FoF, and FoG were not evaluated despite clinical significance. There is a critical need for rigorously designed studies emphasizing motor outcomes and falls prevention to inform clinical practice.

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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