Long-QT Syndrome Induced by the Antiaddiction Drug Ibogaine
Dianne W. M. Hoelen, Wilko Spiering, Gerlof D. Valk
New England Journal of Medicine January 14, 2009 DOI: 10.1056/nejmc0804248 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 31-year-old woman |
| Intervention | Ibogaine |
| Dose | 3.5 g |
| Topics | Ibogaine |
| Citations | 48 |
| Key findings | A single 3.5-g dose of ibogaine was associated with a seizure-like attack and severe QT prolongation (548 msec) with ventricular arrhythmias, indicating significant cardiac risk. |
Abstract
A 31-year-old woman was admitted to the emergency department because of a seizure-like attack after a single 3.5-g dose of ibogaine. ECG showed a severe prolonged-QT interval of 548 msec and ventri...