Gene expression changes in GABA(A) receptors and cognition following chronic ketamine administration in mice.
PLoS One June 21, 2011 DOI: 10.1371/journal.pone.0021328 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Preclinical study Peer reviewed |
|---|---|
| Population | Mice |
| Intervention | Ketamine |
| Topics | Esketamine Ketamine |
| Key points | Chronic ketamine administration changes GABA(A) receptor gene expression and affects cognition in mice, suggesting that alterations in inhibitory neurotransmission may contribute to ketamine-induced cognitive effects. |
Abstract
Gene expression changes in GABA(A) receptors and cognition following chronic ketamine administration in mice.